识别与低血压相关的潜在致病药物:一个范围审查
Nurunnisa Sari1,2, Ulrich Jaehde3, Anna Maria Wermund3
1Institute for Medical Information Processing, Biometry and Epidemiology - IBE, LMU Munich, Munich, Germany.
Archiv der Pharmazie
|November 28, 2024
概括
药物诱导的低血压是一个严重的风险,但意识可以预防它. 本综述详细介绍了与成人低血压相关的抗高血压和非抗高血压药物,以帮助医疗保健专业人员.
科学领域:
- 药理学 药理学是指药理学的学科.
- 临床医学 临床医学
- 药物不良事件 药物不良事件
背景情况:
- 药物诱导的低血压带来了重大风险,包括住院.
- 提高对导致低血压的药物的认识对于预防至关重要.
- 需要对与成人低血压相关的药物的全面概述.
研究的目的:
- 为提供与成人低血压相关的抗高血压和非抗高血压药物的全面概述.
- 确定通常与低血压相关的药物类别.
- 为医疗保健专业人员提供潜在的低血压诱导药物的信息.
主要方法:
- 在MEDLINE,Embase和Cochrane图书馆 (2013年1月 - 2023年5月) 进行了系统的文献搜索.
- 研究的重点是成年人群中的低血压作为药物不良事件,不包括特定群体和条件.
- 从97项符合条件的研究中提取了数据,并将药物分类为类别.
主要成果:
- 在9个类别中确定了26种抗高血压药物和22个类别中确定了158种非抗高血压药物.
- 常见的抗高血压药类包括ACE抑制剂,β-抑制剂和利尿剂.
- 经常涉及的非抗高血压类别是神经质障碍药,α-1抑制剂,二,阿片类药物和抗抑郁药.
结论:
- 医疗保健专业人员必须了解可能导致低血压的非抗高血压药物.
- 这一审查为未来对剂量依赖,药物相互作用和混因素的研究奠定了基础.
- 更好地了解药物诱导的低血压可以提高患者的安全性,减少住院治疗.
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