美国糖尿病患者心脏代谢指数和结石之间的关联:NHANES 2007-2018年
Heng Liu1, Mixue Guo2, Yu Zhou1
1Department of Urology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, PR China.
World journal of urology
|November 28, 2024
概括
心脏代谢指数 (CMI) 升高与糖尿病患者结石风险更高有关. 这种关联在特定收入水平的已婚个人中尤为强烈,突出了预防的目标群体.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學.
- 代谢健康 代谢健康
背景情况:
- 心脏代谢指数 (CMI) 是肥胖和脂质特征的综合指标,越来越多地被认为对代谢健康的作用.
- 结石的患病率越来越令人担忧,特别是在糖尿病患者中,但其与CMI的关联仍未得到充分研究.
研究的目的:
- 调查心脏代谢指数 (CMI) 与糖尿病患者结石患病率之间的关系.
- 确定可能改变这种关联的特定人口或社会经济因素.
主要方法:
- 利用了国家健康和营养检查调查 (2007-2018) 的数据,对一组糖尿病参与者进行了调查.
- 采用多变量逻辑回归,通用添加模型和光滑曲线拟合来分析CMI-结石关联.
- 进行了子组分析和倾向性得分匹配 (PSM),以确保研究结果的可靠性.
主要成果:
- 总共分析了2714名参与者,结石的患病率为16.82%.
- 较高的CMI显著与结石的可能性增加有关 (OR = 1.17;95% CI: 1.06,1.30).
- 这种关联在已婚/有伴侣的个人中更为明显,贫困收入比率 (PIR) 介于1.5至3.5之间 (相互作用的P<0.05).
结论:
- 较高的心脏代谢指数 (CMI) 是糖尿病患者结石的重要危险因素.
- 特定的子组,包括中等贫困水平的已婚/伴侣个人,表现出更强的关联,建议有针对性的预防策略.
- 这些发现强调了代谢健康监测对于糖尿病人群中预防结石的重要性.
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