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Updated: May 10, 2026

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Published on: July 11, 2013

在2024年,EMBL的欧洲生物信息学研究所 (EMBL-EBI)

Matthew Thakur1, Catherine Brooksbank1, Robert D Finn1

  • 1European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, CB10 1SA, UK.

Nucleic acids research
|November 28, 2024
PubMed
概括

欧洲生物信息学研究所 (EMBL-EBI) 提供重要的公共生物分子数据服务. 这篇概述强调了他们全球科学数据资源产品的最新进展.

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Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...