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Updated: Jun 6, 2025

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线素激活蛋白激酶酸酶-5是TGF-β通过JNK依赖途径信号传输所需的

Sam Dorry1, Sravan Perla1, Anton M Bennett1,2

  • 1Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut, USA.

Molecular and cellular biology
|November 28, 2024
PubMed
概括

线素激活蛋白激酶酸酶-5 (MKP-5) 通过调节转化生长因子-β (TGF-β) 信号传递,促进组织纤维化. MKP-5的非激活阻断了TGF-β通路的激活,揭示了纤维化中的新机制.

关键词:
基因激活的蛋白质激酶激酶是由基因激活的.细胞信号传递是细胞的信号传递.蛋白质酸酶是一种蛋白质酸酶蛋白质的酸化是蛋白质的酸化.信号传导的信号传导.

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