在患有炎症性肠道疾病的患者中进行大肠切除术时未被检测到的发育不良. 我们错过了什么?
Erica Centorrino1,2, Davide Ferrari3,4, William S Harmsen5
1Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Inflammatory bowel diseases
|November 28, 2024
概括
在炎症性肠病 (IBD) 患者中,5.4%的失塑性病变在结肠镜检查期间没有发现,只有在手术期间发现. 实现内镜缓解对于检测这些病变至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠手术 结肠直肠手术
- 在瘤学瘤学.
背景情况:
- 炎症性肠病 (IBD) 患者面临着结直肠张症和癌症的风险增加.
- 监测结肠镜的目的是检测出失生症,但有些病变仍然未被检测到.
研究的目的:
- 为了确定IBD患者经过胆管切除术的遗漏失生性病变的发生率.
- 在结肠镜检查期间识别与未检测到的发育不良相关的因素.
主要方法:
- 对1320名接受集体切除术的IBD患者 (2003-2022) 的回顾性分析.
- 将手术前5年内结肠镜检查结果与手术病理学报告进行比较.
- 识别与遗漏发育不良相关的因素.
主要成果:
- 5.4%的患者患有只在手术期间检测到的失塑性病变.
- 与遗漏发育不良相关的因素包括中度/严重的内镜疾病活动和较短的疾病持续时间.
- 内镜缓解,先前发育不良检测,监视结肠镜检查和更长的疾病持续时间与检测到的发育不良有关.
结论:
- 临床医生必须认识到IBD患者,特别是活跃的内镜疾病患者的错过失生性损伤的风险.
- 实现内镜缓解对于改善检测"隐形"失塑性病变至关重要.
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