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Updated: Jun 6, 2025

A Chromatin Immunoprecipitation Assay to Identify Novel NFAT2 Target Genes in Chronic Lymphocytic Leukemia
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在急性髓性白血病中准染色质修饰复合物

Alexandra Schurer1,2, Shira G Glushakow-Smith1,2, Kira Gritsman1,2,3,4,5

  • 1Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, United States.

Stem cells translational medicine
|November 28, 2024
PubMed
概括

染色质修饰失调驱动急性髓性白血病 (AML) 复发. 针对menin-KMT2A和多镇压复合体 (PRC1/2) 显示出 AML 治疗和克服耐药性的前景.

关键词:
在HOXA/BB中使用.这就是Meis1的意义.在 KMT2A 中.KMT2A-重新安排没有NPM1cc.在PRC1中,在 PRC2 中,PRC2 是 PRC2 的第一个类型.急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.在这种情况下,染色染色素基因组 基因组 基因组脑膜抑制是一种抑制作用.

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