在患有胃癌的亚洲人中呈现,治疗和生存
Patrick L Quinn1, Fode Tounkara1, Kunika Chahal2
1Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.
The Journal of surgical research
|November 28, 2024
概括
与非西班牙裔白人 (NHW) 患者相比,亚洲胃癌 (GC) 患者,特别是东亚人,表现更好,生存率更高. 这项研究强调了这些子群体的改善表现和治疗.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 健康差异 在健康上的差异
背景情况:
- 胃癌 (GC) 在全球范围内不成比例地影响亚洲人口.
- 有限的数据存在于美国不同亚裔美国人亚裔人口中的GC结果.
- 了解这些差异对于有针对性的癌症护理至关重要.
研究的目的:
- 分析和比较各种亚裔美国人亚群与非西班牙裔白人 (NHW) 患者的胃癌 (GC) 结果.
- 为了识别疾病呈现,治疗和生存的差异.
- 为解决GC健康差异的策略提供信息.
主要方法:
- 利用国家癌症数据库 (2004-2020年) 来识别GC患者.
- 按地区分类亚洲患者,重点关注东亚亚亚组.
- 使用后勤回归,根据人口,临床和社会经济因素进行调整.
主要成果:
- 与NHW患者相比,东亚患者的非转移性呈现 (OR 1.59) 和治愈切除 (OR 1.52) 的几率较高.
- 总体而言,亚洲亚种群的整体死亡风险明显较低 (P < 0.001).
- 来自东方,东南亚和南亚以外的患者显示延迟治疗的几率增加 (OR 1.29).
结论:
- 与NHW患者相比,亚洲GC患者通常具有更好的结果,主要由东亚亚亚组驱动.
- 所有分析的亚洲亚群都显示出相对于NHW患者的生存率有所改善.
- 这些发现强调了在癌症研究中对亚种群进行特定分析的重要性.
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