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β1-整蛋白控制IGF-1R内部化和细胞内信号传递

Niamh McDermott1, Stephen O'Shea1, Leonie Rieger1

  • 1Cell Biology Laboratory, School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.

The Journal of biological chemistry
|November 28, 2024
PubMed
概括

在Tyr1250/1251中胰岛素样生长因子1受体 (IGF-1R) 的酸化驱动癌细胞迁移,并通过β1-整合素 (ITGB1) 信号增强,促进瘤的攻击性.

关键词:
乳腺癌 乳腺癌 乳腺癌癌症 癌症 癌症 癌症 癌症细胞粘附 细胞粘附胰岛素样生长因子1受体 (IGF-1R)整体的整体是整体的酸化的方法是:光化.接收器内部化 接收器内部化接收器的结构-功能.细胞下部位的位置转化转化转化转化转化转化转化转化

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