2型糖尿病患者同时进行有氧和力量训练的效果:贝叶斯对照和剂量反应元分析
Han Xue1, Yuehui Zou2, Shijie Zhang3
1Nantong University, Nantong, Jiangsu, China.
BMJ open diabetes research & care
|November 28, 2024
概括
同时训练 (CT) 在2型糖尿病患者中显著改善血糖控制,降低HbA1c和禁食血糖. 为了获得最大的益处,确定了1030METs-min的最佳每周剂量.
科学领域:
- 运动生理学 运动生理学
- 代谢疾病 代谢疾病
- 临床研究 临床研究
背景情况:
- 2型糖尿病 (T2D) 的管理通常涉及生活方式干预.
- 同步训练 (CT),结合有氧和力量炼,是T2D的一个有希望的方法.
- 对T2D患者的最佳CT剂量需要进一步调查.
研究的目的:
- 评估CT对T2D患者血糖控制和其他健康标志物的疗效.
- 确定CT之间的剂量反应关系及其在T2D中的影响.
- 确定最有效的CT治疗方案,以改善T2D患者的健康结果.
主要方法:
- 在PubMed,Embase,Web of Science和Cochrane图书馆系统搜索到2024年3月的RCT.
- 包括23个RCT,其中有1948名参与者 (52%是男性,年龄在50-65岁之间).
- 贝叶斯阶层随机效应元分析 (对和剂量反应) 来分析HbA1c,FBG,BMI,体脂,血压和VO2max等结果.
主要成果:
- 通过CT显著降低了HbA1c (MD=-0.48%) 和FBG (MD=-0.48 mmol/L).
- 在CT剂量和HbA1c降低之间发现了非线性剂量反应关系.
- 最佳CT剂量确定为1030METs-min/week,推为270分钟的中度或160分钟的强烈强度.
结论:
- CT有效改善2型糖尿病患者的关键健康指标.
- 一个特定的每周训练量 (1030 METs-min) 优化了HbA1c的降低.
- 个人化CT处方,考虑到强度和持续时间,推用于T2D管理.
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