澳大利亚患有抑郁症的青少年的一种基于正念,认知,社会,数字的复发预防干预:Rebound随机对照试验的研究协议
Shaminka N Mangelsdorf1,2, Daniela Cagliarini3,2, Yong Yi Lee4,5,6
1Orygen, Parkville, Victoria, Australia.
BMJ open
|November 28, 2024
概括
这项研究测试了Rebound,一种在线社交疗法,与常规增强治疗 (TAU) 相比,用于预防年轻人重度抑郁症 (MDD) 复发. 结果将决定Rebound是否改善了管理抑郁症状的结果.
科学领域:
- 心理健康 心理健康
- 数字治疗学数字治疗学
- 青少年和年轻人的精神病学
背景情况:
- 重度抑郁症 (MDD) 构成了相当大的负担,在青少年和年轻人中复发率很高.
- 反复出现的抑郁症会加剧严重程度,并变得抗治疗.
- 一个新的调节在线社会治疗平台Rebound被开发来解决复发问题.
研究的目的:
- 为了评估反弹平台加上通常治疗 (TAU) 与单独增强的TAU相比的疗效.
- 为了确定Rebound是否可以预防复发,并管理MDD年轻人的抑郁症状超过18个月.
- 调查反弹的潜在治疗机制,包括正念,自我同情,社会支持和反减少.
主要方法:
- 一个评估者掩盖的随机对照试验,涉及255名年龄在14-27岁的参与者,至少有一次之前的MDD发作.
- 参与者被随机分配,接受反弹加TAU或单独增强TAU18个月.
- 主要结局是18个月后抑郁复发,使用DSM-5 (SCID-5-RV) 结构化临床访谈进行评估.
主要成果:
- 数据收集和分析正在进行中; 结果正在等待.
- 该研究旨在检测复发率和抑郁症状严重程度的差异.
- 二次结果包括复发/缓解的时间,焦虑症状和经济影响.
结论:
- 这项研究将提供关键的见解,以了解数字干预措施的有效性,以防止MDD在年轻人群中的复发.
- 调查结果将为开发和实施可访问,基于证据的心理健康支持提供信息.
- 这项研究旨在增强MDD患者的长期康复和功能结果.
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