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Updated: Jun 6, 2025

Molecular Modulation by Lentivirus-Delivered Specific shRNAs in Endoplasmic Reticulum Stressed Neurons
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作为一个有前途的新型TREM2激动剂,脱水胺减轻神经炎症

Lin Li1, Nan Xu1, Yulin He2

  • 1State Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao, China.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
|November 28, 2024
PubMed
概括

脱水素胺 (DHE) 激活TREM2,通过抑制促炎细胞因子和恢复线粒体功能来减少神经炎症. 这种天然类化合物显示出作为治疗中枢神经系统疾病的治疗剂的前景.

关键词:
19,20-脱水族维他胺在 NF-κBB 中.在NLRP3中,NLRP3是NLRP3中的一个.神经炎症是一种神经炎症.在TREM2中,我们可以使用TREM2.

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