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Updated: Jun 29, 2026

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无活动介导的分子适应:从身体活动减少的临床前模型的见解

Alice Meyer1, Nicole Kim2, Melissa Nguyen3

  • 1Department of Anatomy, College of Graduate Studies, Midwestern University, Downers Grove, Illinois, USA.

Physiological reports
|November 28, 2024
PubMed
概括

减少体力活动迅速导致代谢不灵活性和胰岛素抵抗,甚至在身体组成发生变化之前. 这项研究确定了与不活动相关的肌肉关键基因变化.

关键词:
减少体力活动 减少体力活动身体不活动.骨肌肉的新陈代谢骨肌肉转录基因组转录基因组

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Cells can adapt to environmental changes to maintain function and avoid injury, a process called cellular adaptation. Adapted cells exist in a reversible intermediate state with changes in size, number, phenotype, metabolism, or function. These responses help cells meet altered physiological or pathological demands; for example, enlargement of breast and uterine tissues during pregnancy. Early adaptations may enhance function, but persistent stress eventually causes tissue damage.Types of...