相关实验视频

Updated: Jun 6, 2025

Super-Resolution Microscopy of the Synaptonemal Complex Within the Caenorhabditis elegans Germline
09:14

Super-Resolution Microscopy of the Synaptonemal Complex Within the Caenorhabditis elegans Germline

Published on: September 13, 2022

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C. elegans配对中心的结构基础是ZIM/HIM-8家族蛋白质的DNA结合特异性

Meili Li1, Chengming Zhu1, Zheng Xu2

  • 1MOE Key Laboratory for Cellular Dynamics, Hefei National Laboratory for Physical Sciences at the Microscale, The First Affiliated Hospital of USTC, Biomedical Sciences and Health Laboratory of Anhui Province, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

Nature communications
|November 28, 2024
PubMed
概括

在C. elegans的染色体配对中心的特定DNA图案招募了化蛋白. 结构研究揭示了HIM-8,ZIM-1和ZIM-2蛋白质如何识别这些DNA序列,澄清了半分裂的一个关键步骤.

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In Situ Detection of Ribonucleoprotein Complex Assembly in the C. elegans Germline using Proximity Ligation Assay08:56

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DamID-seq: Genome-wide Mapping of Protein-DNA Interactions by High Throughput Sequencing of Adenine-methylated DNA Fragments09:14

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