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Updated: May 13, 2026

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
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Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology

Published on: December 15, 2017

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在固态发酵条件下,基于人工智能的优化,用于Streptomyces violaceoruber在固态发酵条件下的细胞外L-glutaminase自由L-asparaginase生产

Noura El-Ahmady El-Naggar1, Ragaa A Hamouda2,3, Naglaa Elshafey4

  • 1Department of Bioprocess Development, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), New Borg El-Arab City, 21934, Alexandria, Egypt. nouraalahmady@yahoo.com.

Scientific reports
|November 28, 2024
PubMed
概括

链杆菌 (Streptomyces violaceoruber) NEAE-99产生无谷氨酶的L-阿斯巴拉金酶,这是急性淋巴细胞白血病的关键药物. 使用人工神经网络 (ANN) 和中央复合设计 (CCD) 的优化最大限度地提高了酶生产.

关键词:
人工神经网络的人工神经网络中心复合设计设计L-阿斯巴拉金酶; 链状菌; 识别优化优化 优化优化

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