在美国成年人中对诊断阻塞性睡眠呼吸暂停的人类指数进行比较分析
Wenjia Liu1, Shangyi Song2, Hongguo Zhang1
1Psychology of Traditional Chinese Medicine, Heilongjiang University of Traditional Chinese Medicine, Heilongjiang, 150006, China.
Scientific reports
|November 28, 2024
概括
肥胖影响阻塞性睡眠呼吸暂停 (OSA) 的风险. 腰围 (WC) 和体重指数 (BMI) 是早期OSA检测和风险评估的强有力的指标,特别是在女性中.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 公共卫生 公共卫生
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 与肥胖有关,脂肪分布起着关键作用.
- 评估肥胖需要考虑整体体重和局部脂肪沉积.
研究的目的:
- 评估阻塞性睡眠呼吸暂停 (OSA) 的各种人类指标的诊断性能.
- 为了比较不同肥胖指数在预测跨性别OSA风险方面的有效性.
主要方法:
- 一项横截面研究分析了来自NHANES周期 (2005-2008,2015-2018) 的8966名参与者.
- 使用后勤回归和ROC曲线分析来评估人体指数 (BMI,WC,BRI,VAI,LAP) 和OSA之间的关联.
- 计算AUC值以确定诊断性能,并使用DeLong的测试进行性别比较.
主要成果:
- 腰围 (WC) 和体重指数 (BMI) 被确定为OSA风险的最强的诊断指标,经过同变量调整后.
- 与男性相比,ROC分析显示女性的WC和BMI诊断性能更高 (AUC:0.651-0.653),而男性的AUC:0.616-0.619).
- 其他指数如BRI,VAI和LAP显示OSA的诊断能力较弱.
结论:
- WC和BMI是OSA早期检测和风险分层的实用和有效工具.
- 这些指数显示出两性之间强大的诊断能力,女性在预测能力方面略有优势.
- 研究结果支持WC和BMI在治疗OSA患者中的临床实用性.
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