根据出生时的妊娠年龄,根据病因学特征的早产新生儿的产后生长
Paola Roggero1, Irina Ryumina2, Robert B Gunier3
1Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Pediatric research
|November 28, 2024
概括
过早分娩的原因各不相同,不同影响婴儿的成长. 产后生长部分独立于胎儿生长,特别是在晚期早产的婴儿中.
科学领域:
- 新生儿科学 新生儿科学
- 儿科生长与发展 儿科生长与发展
- 围产儿医学 围产儿医学
背景情况:
- 过早分娩是导致婴儿死亡和发病的主要原因.
- 过早出生的婴儿面临不理想生长,发育问题和神经发育受损的风险.
- 过早分娩是一种异质的疾病,具有不同的病因和结果.
研究的目的:
- 研究早产和早产后生长的特定病因之间的关系.
- 分析不同妊娠年龄类别 (非常,中度,晚期早产) 的产后生长轨迹.
- 为了确定产后生长是否受到各种早产子组的胎儿生长 (出生大小) 的影响.
主要方法:
- 在15家医院进行的前性,跨国队列研究.
- 包括2320个单身和1180个双胞胎.
- 使用INTERGROWTH-21st早产产后生长标准 (z-scores) 进行的连续人类测量测量.
主要成果:
- 与"没有主要疾病"参考组相比",围产性败血症"",怀疑IUGR"和"胎儿痛苦"子组的婴儿在出生后的生长率较低.
- 这种生长模式的差异在晚期早产婴儿中持续存在,即使在调整出生体重z-score之后.
- 发现产后生长部分独立于胎儿生长,特别是在晚期早产的婴儿中.
结论:
- 从病因上定义的早产子组的贡献及其生长模式在早产类别之间有所不同.
- 产后生长轨迹受到早产的潜在原因的影响.
- 相当一部分早产婴儿,尤其是晚期早产婴儿,在产后表现出不仅仅取决于他们出生时的体型的生长.
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