哪些饮食模式可以抵御非酒精性脂肪肝疾病? 对观察性和干预性研究进行系统审查
Farnush Bakhshimoghaddam1,2, Daniel Baez3, Neda Dolatkhah4
1Nutrition and Metabolic Diseases Research Center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
健康的饮食模式,如地中海或低碳水化合物饮食,可以帮助预防和管理非酒精性脂肪肝疾病 (NAFLD). 相反,西方饮食中含有不健康食品的高含量与NAFLD风险增加有关.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 非酒精性脂肪肝 (NAFLD) 是一个日益严重的全球健康挑战.
- 饮食模式显著影响NAFLD的发展,预防和治疗.
- 饮食模式分析考虑了食品成分的累积效应和相互作用.
研究的目的:
- 系统地审查观察研究和干预试验.
- 确定各种饮食模式与NAFLD之间的联系.
- 通过饮食修改,为NAFLD预防和治疗策略提供信息.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 在PubMed,Embase和Cochrane图书馆的数据库中进行了搜索.
- 包括对成年人前期和后期饮食模式的研究;使用纽卡斯尔-太华或贾达德尺度评估质量.
主要成果:
- 审查了来自16个国家的27项观察研究和16项干预研究.
- 地中海和DASH饮食可以预防/改善NAFLD.
- 西方饮食与NAFLD风险增加有关;低碳水化合物饮食显示出预防和治疗的希望.
结论:
- 植物性或改性宏观营养素饮食,包括低碳水化合物饮食,可以降低NAFLD的风险和进展.
- 需要对低脂肪饮食和NAFLD管理的特定脂肪类型进行进一步的研究.
- 未来研究的建议旨在填补NAFLD饮食管理方面的知识空白.
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