中年城市成年人的睡眠模式,全球心理状态和死亡风险
May A Beydoun1, Hind A Beydoun2,3, Michael F Georgescu1
1Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, NIA/NIH/IRP, Baltimore, MD, USA.
Journal of Alzheimer's disease : JAD
|November 29, 2024
概括
全球心理状况不佳会增加死亡风险,尤其是睡眠质量好时. 相反,睡眠质量差与具有更好的认知功能的人的死亡风险更高有关. 需要进一步的研究.
科学领域:
- 老年学是一门学科.
- 睡眠科学 睡眠科学
- 公共卫生 公共卫生
背景情况:
- 睡眠,认知功能和死亡率可能相互关联.
- 了解这些关系对于健康的衰老至关重要.
研究的目的:
- 研究睡眠,全球精神状态和死亡风险之间的复杂相互作用.
- 探索睡眠质量和认知功能的潜在相互作用对死亡率的影响.
主要方法:
- 分析了来自1364名参与者健康老龄化在整个生命周期 (HANDLS) 跨越多样性的邻里研究的数据.
- 利用考克斯的比例危险模型和四向分解模型来评估睡眠模式和全球心理状态.
- 研究了匹兹堡睡眠质量指数 (PSQI) 评分,认知状态和死亡率之间的关联,平均随访时间为8.2年.
主要成果:
- 总体PSQI得分增加1个单位最初与死亡风险增加7%有关.
- 发现了显著的相互作用:睡眠质量差与总体精神状况较好的个体的死亡风险有关.
- PSQI得分对死亡率的总影响是积极的,主要是受控的直接影响. 在女性中,认知状态对死亡率有影响,部分是通过睡眠延迟和全球PSQI得分.
结论:
- 全球心理状况不佳与死亡风险增加有关,特别是当睡眠质量更好时.
- 相反,更好的睡眠质量与较差认知功能的个体的较低死亡风险有关.
- 建议进行长度研究,重复测量睡眠和认知,以证实这些发现.
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