早期阿尔茨海默病的记忆无意识症:一个记忆临床研究研究
Thomas Benke1, George Karagiannis1
1Clinic of Neurology, Medical University, Innsbruck, Austria.
Journal of Alzheimer's disease : JAD
|November 29, 2024
概括
记忆无意识,或对记忆丧失的不意识,在早期阿尔茨海默病 (AD) 中很常见. 这种不意识,加上记忆力差,使得阿兹海默症患者与轻度认知障碍或正常认知的患者有所区别.
科学领域:
- 神经学 神经学
- 认知科学 认知科学
- 心理学 心理学 心理学
背景情况:
- 在阿尔茨海默氏病 (AD) 中,对记忆障碍 (无意识) 的不意识是普遍存在的.
- 以前的研究表明,关于其呈现,评估和认知联系的发现各不相同.
- 了解记忆意识对于管理AD患者至关重要.
研究的目的:
- 预测和在线评估早期阿兹海默症患者的记忆意识.
- 在AD,轻度认知障碍 (MCI) 和正常认知 (NC) 组中比较记忆意识.
主要方法:
- 参与者包括来自记忆诊所的门诊患者:AD,MCI和NC组.
- 基于绩效的评估测量了自我感知的记忆能力.
- 通过将自我评价与客观神经心理测试分数 (CERAD-NB) 进行比较,计算出一个无意识率.
主要成果:
- 几乎一半的阿兹海默症患者表现出记忆无知症 (自我高估),在MCI中罕见,在NC中不存在.
- 阿尔茨海默病患者的预测和在线自我评估准确性不佳.
- 过度估计记忆的人年龄较大,受教育程度较低,认知得分较差,特别是在执行和记忆功能方面.
结论:
- 记忆无意识症是早期AD的标志,与认知能力下降一起.
- 基于表现的记忆性无意识的评估区分了早期的AD与MCI和NC.
- 评估记忆自我评估在记忆诊所中至关重要,它补充了临床和认知评估.
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