相关实验视频

Updated: Jun 6, 2025

Combining Mitotic Cell Synchronization and High Resolution Confocal Microscopy to Study the Role of Multifunctional Cell Cycle Proteins During Mitosis
08:33

Combining Mitotic Cell Synchronization and High Resolution Confocal Microscopy to Study the Role of Multifunctional Cell Cycle Proteins During Mitosis

Published on: December 5, 2017

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染色体对齐和Kif18A的作用依赖于对Cdk1活动的螺杆局部控制

Angela Flavia Serpico1, Caterina Pisauro2, Asia Trano1

  • 1Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), University of Naples "Federico II", Naples, Italy.

Frontiers in cell and developmental biology
|November 29, 2024
PubMed
概括

这项研究表明,通过调节Kif18A活性,抑制的环林依赖激酶1 (i-Cdk1) 对于正确的染色体对齐至关重要. 恢复i-Cdk1可以纠正形缺陷,改善Kif18A局部化,提供潜在的癌症治疗见解.

关键词:
一个小小的小小的.没有积症.癌症的脆弱性 癌症的脆弱性染色体对齐是因为染色体对齐.在i-Cdk1中微核是微核中的一个.螺旋组合组件的组合

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