β-粉样蛋白的翻译后修饰调节其对细胞机械特性的影响,并影响细胞骨信号级联

Kseniya B Varshavskaya1, Evgeny P Barykin1, Roman V Timoshenko2

  • 1Engelhardt Institute of Molecular Biology, Moscow, Russia.

PubMed
概括

贝塔-粉样蛋白 (Aβ) 的翻译后修饰会影响阿尔茨海默病 (AD) 的发病. 不同的Aβ异型通过不同的信号通路改变神经元细胞机制和活性氧物种 (ROS) 水平.

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