中国老年人认知功能和虚弱的轨迹:一项纵向研究
Xiaoyi Ji1, Yue Wu1, Zijie Gu1
1West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Frontiers in aging neuroscience
|November 29, 2024
概括
认知障碍和虚弱通常在老年人中共同发展. 识别共同的风险因素是早期干预的关键,并可能逆转脆弱性,以防止认知能力下降.
科学领域:
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
- 认知科学 认知科学
背景情况:
- 认知障碍和虚弱是老年人群中普遍存在的疾病.
- 了解它们的共同发展对于有针对性的干预至关重要.
- 早期检测策略可以使高风险个体受益.
研究的目的:
- 识别认知功能和虚弱的不同共同发展轨迹.
- 探索与这些轨迹相关的人口和临床特征.
主要方法:
- 分析了来自8,418名55岁以上 (2011-2018) 的中国成年人数据.
- 利用基于组的双轨道建模和物流回归.
- 确定了轨迹组,并评估了相关的风险因素.
主要成果:
- 确定了两个主要轨迹:"持续强" (76.12%) 和"持续严重" (23.88%).
- 与"持续严重"组相关的因素包括女性性别,年龄较大,教育程度较低,农村居住,未婚状态和并发性疾病 (高血压,糖尿病,视力/听力障碍,牙损失).
结论:
- 在中国老年人中,认知功能和虚弱之间存在着显著的共同发展模式.
- 虽然认知障碍可能是不可逆转的,但脆弱性可能是可逆的.
- 由于共同的轨迹,早期检测和干预至关重要,旨在防止认知衰退.
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