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在带血中表征DNA甲基化和基甲基化,并使用Illumina EPIC阵列识别性别特异性差异

Rebekah L Petroff1, Dana C Dolinoy1,2, Vasantha Padmanabhan1,3,4

  • 1Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.

Epigenetics reports
|November 29, 2024
PubMed
概括

区分DNA甲基化 (5-mC) 和基甲基化 (5-hmC) 是至关重要的. 这项针对婴儿带血的研究发现,总甲基化中的性别特异性差异显著,但单独对5-mC和5-hmC的甲基化差异较小.

关键词:
5-hmC是一种5HmC.5mC 的 5mC.通过DNA氧甲基化.通过DNA甲基化.在Illumina的EPIC阵列中,表观遗传学是指表观遗传学.

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