治疗的民族药理学视角:一个更新的审查
Sunishtha Kalra1,2, Saurabh Bhatia3,4, Ahmed Al Harrasi3
1Department of Pharmacology, Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra, Haryana 136119, India.
Scientifica
|November 29, 2024
概括
本综述汇编了使用全球药用植物的传统治疗方法. 它强调了114种植物,为发现新的抗药物提供了宝贵的资源.
科学领域:
- 民族植物学 民族植物学
- 药理学 药理学是指药理学的学科.
- 神经学 神经学
背景情况:
- 在人类历史上,植物一直被用于药用目的.
- 传统知识包含了关于各种疾病,包括的植物性疗法的重要信息.
- 民族植物学研究对于从自然来源发现潜在的治疗剂至关重要.
研究的目的:
- 系统地审查和记录不同文化中用于治疗的传统药用植物.
- 编制植物物种,它们的部分,提取物和的传统应用的全面清单.
- 为进一步科学研究药用植物新型抗药物提供基础.
主要方法:
- 使用主要科学数据库 (PubMed,Scopus,Web of Science等) 进行了全面的文献调查. 和参考教科书.
- 在文献搜索中使用了""",治疗的药用植物"和"传统抗药"等关键词.
- 提取的数据包括植物生物名称,使用的部分,提取物,剂量,实验模型和结果,重点关注114种植物.
主要成果:
- 该审查确定并详细介绍了传统上用于治疗的114种植物物种.
- 收集了有关植物部位,提取物,化合物,剂量和实验发现的信息.
- 对15种特定的药用植物进行了更详细的研究,以了解它们的抗潜力.
结论:
- 编制的药用植物清单对寻找新型抗药物的研究人员来说是一个宝贵的资源.
- 这一综述强调了 etnobotanical 数据在神经疾病的药物发现的重要性.
- 需要对这些传统疗法进行进一步的实验查和验证,以确认它们的有效性和安全性.
相关概念视频
01:14Antiepileptic Drugs: Glutamate Antagonists
283
Glutamate is a fundamental neurotransmitter in the central nervous system, playing a vital role in neuronal communication and various cognitive processes. Glutamate stands as the principal excitatory neurotransmitter in the brain. Its presence is crucial for the communication between neurons, underpinning essential processes such as synaptic transmission, neuronal excitability, and plasticity. These functions are vital for higher-order cognitive processes, including learning and memory. The...
283
01:18Antiepileptic Drugs: GABAergic Pathway Potentiators
333
γ-aminobutyric acid or GABA, plays a pivotal role as an inhibitory neurotransmitter in the brain. GABA pathway potentiators, also known as GABAergic drugs, are a class of pharmaceutical agents designed to enhance the functioning of the GABAergic system. These medications primarily treat epilepsy, a neurological disorder characterized by recurrent seizures.
The key GABA pathway potentiators used in epilepsy management are as follows.
Benzodiazepines are a well-known class of drugs used for...
The key GABA pathway potentiators used in epilepsy management are as follows.
Benzodiazepines are a well-known class of drugs used for...
333
01:24Arteries of the Lower Limbs
177
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
177
01:08Antiepileptic Drugs: Sodium Channel Blockers
426
Antiepileptic drugs are specialized medications that prevent seizures in individuals diagnosed with epilepsy. These drugs primarily function by blocking the movement of sodium ions through channels in the neuronal membrane, inhibiting the repetitive firing of action potentials often associated with seizures.
Sodium channel blockers modulate ion channels, particularly voltage-gated sodium channels. They block only sodium ion movement.
Among the most commonly prescribed antiepileptic drugs are...
Sodium channel blockers modulate ion channels, particularly voltage-gated sodium channels. They block only sodium ion movement.
Among the most commonly prescribed antiepileptic drugs are...
426
01:17Antiepileptic Drugs: Calcium Channel Blockers
320
Calcium channel blockers, a class of antiepileptic drugs, regulate the flow of calcium ions within neurons.
Calcium channel blockers exert their antiepileptic effects by targeting T-type calcium channels, which are integral to transmitting nerve signals in the central nervous system. These channels allow the passage of calcium ions, which are vital for neuronal communication. By inhibiting T-type calcium channels, calcium channel blockers effectively reduce the release of neurotransmitters and...
Calcium channel blockers exert their antiepileptic effects by targeting T-type calcium channels, which are integral to transmitting nerve signals in the central nervous system. These channels allow the passage of calcium ions, which are vital for neuronal communication. By inhibiting T-type calcium channels, calcium channel blockers effectively reduce the release of neurotransmitters and...
320
01:20Antiepileptic Drugs: Potassium Channel Activators
146
Ezocgabine or retigabine, an antiepileptic drug of remarkable efficacy, has revolutionized the management of seizures. It is a potassium channel activator, explicitly targeting the family of Q subtype potassium channels. It enhances the transmembrane potassium currents, regulating neuronal excitability. This action stabilizes the resting membrane potential, a pivotal factor in mitigating the hyperexcitability that characterizes epilepsy.
Ezogabine has gained approval as an adjunctive treatment...
Ezogabine has gained approval as an adjunctive treatment...
146