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Updated: May 7, 2026

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对单细胞Hi-C嵌入方法的一小部分回顾

Rui Ma1, Jingong Huang2, Tao Jiang2,3

  • 1Department of Statistics, University of California Riverside, 900 University Ave., Riverside, 92521, CA, USA.

Computational and structural biotechnology journal
|November 29, 2024
PubMed
概括

本综述探讨了用于分析3D基因组组织的单细胞Hi-C (scHi-C) 嵌入方法. 它对规范化,归算和细胞聚类的技术进行了基准测试,帮助研究人员选择最佳工具.

关键词:
缩小尺寸的缩小方式嵌入式 嵌入式 嵌入式基因组架构 基因组架构一个单细胞的Hi-C.

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Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
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