关于B细胞对多发性硬化症的贡献的全球观点:深入检查和评估
Xinzhan Jiang1, Hongyu Zhang2, Yongtao Liu1
1Department of Neurobiology, Harbin Medical University, Harbin, China.
Frontiers in immunology
|November 29, 2024
概括
这项文献计量研究揭示了多发性硬化症 (MS) B细胞研究的关键趋势和新兴领域. 新出现的焦点包括脑膜炎,爱斯坦-巴尔病毒和用于MS治疗的激酶抑制剂.
科学领域:
- 免疫学 免疫学 免疫学
- 神经科学是一个神经科学.
- 图书统计学 图书统计学
背景情况:
- 多发性硬化症 (MS) 是一种慢性自身免疫性疾病,其中B细胞在其发病过程中发挥着重要作用.
- 尽管人们越来越感兴趣,但缺乏对MSB细胞的研究趋势和焦点的全面分析.
- 这项研究为未来对MS的机理学研究提供了宝贵的参考.
研究的目的:
- 想象和分析与多发性硬化症 (MS) 相关的B细胞研究中的研究趋势和焦点.
- 确定该领域的关键研究人员,机构,国家和新兴主题.
- 为MS领域的研究人员提供全面和客观的视角.
主要方法:
- 从科学网络核心集合 (2014-2023) 获取的图书统计数据.
- 分析使用VOSviewer和CiteSpace进行共同作者,共同发生和引用分析.
- 从全球5,337个机构的1,041个期刊中检查了5,578篇文章.
主要成果:
- 美国在出版量方面处于领先地位;Amit Bar-Or是最有影响力的作者;Frontiers in Immunology是顶级期刊.
- 研究越来越多地关注B细胞在中枢神经系统 (CNS) 和抗B细胞治疗机制中的作用.
- 新兴趋势突出显示了脑膜炎症,激酶抑制剂和爱斯坦-巴尔病毒 (EBV) 在MS研究中的作用.
结论:
- 图书统计分析确定了MS B细胞研究 (2013-2024) 中的关键趋势和新兴领域.
- 这些发现强调了B细胞在MS病变发生过程中的多方面的作用,特别是在中枢神经系统中.
- 脑膜炎症,EBV感染和激酶抑制剂是对MS的有希望的未来研究途径.
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