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在患有急性淋巴细胞白血病的儿科患者中,新型基因组变异影响了甲特雷克萨特延迟清除

Jung Yoon Choi1,2, Hoshik Kwon3, Hyery Kim4

  • 1Department of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.

Frontiers in pharmacology
|November 29, 2024
PubMed
概括

这项研究确定了包括 ENG 和 PKD1L2 在内的遗传变异,与儿科白血病患者高剂量甲状腺素清除延迟相关. 这些发现可能有助于减少MTX的毒性.

关键词:
急性淋巴细胞白血病急性淋巴细胞白血病不良反应是不良反应.孩子们的孩子们的孩子们的孩子们.延迟的清除时间甲基特雷克萨酸盐的使用方法儿科 儿科 儿科药物基因组学 药物基因组学

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