粘附度的变化作为计算方法的函数
Jeffrey M Rohay1, Jacqueline M Dunbar-Jacob1
1University of Pittsburgh, School of Nursing, Pittsburgh, PA, United States.
Frontiers in pharmacology
|November 29, 2024
概括
药物坚持率根据计算方法 (药片计数,每日,时间) 有显著差异. 变量也不同,突出了在研究中定义遵守措施的重要性.
科学领域:
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 药物坚持对于管理并发病状况至关重要.
- 现有的药物坚持的操作定义各不相同,可能会影响研究结果.
研究的目的:
- 为了比较药物坚持的不同操作定义.
- 在患有并发性疾病的患者中检查这些指标的患者内部变异性.
主要方法:
- 通过电子监控的坚持数据使用三个方法进行了分析:PILLCOUNT,DAILY和TIMING.
- 这些措施被汇总成六个30天的时间段.
- 针对DAILY和TIMING的遵守,计算了患者内部的变化.
主要成果:
- 坚持率各不相同:每日计数 (89%-92%),每日计数 (79%-85%) 和定时计数 (62%-68%).
- 对TIMING (29%-35%) 的患者内部变异性高于DAILY (20%-25%).
结论:
- 坚持定义的选择显著影响结果和解释.
- 可变性测量提供了对坚持模式的更全面的了解.
- 未来的研究应该具体说明所使用的坚持计算方法.
相关概念视频
Variability: Analysis
126
Measures of variability are statistical metrics that reveal the dispersion pattern within a dataset. They are pivotal in biostatistics, providing insights into the heterogeneity within health and biological data. Variability signifies the degree to which data points diverge from one another, helping researchers understand the potential range of values and associated uncertainty within the data.
The range is a simple measure of variability, indicating the difference between the highest and...
The range is a simple measure of variability, indicating the difference between the highest and...
126
Statistical Analysis: Overview
6.1K
When we take repeated measurements on the same or replicated samples, we will observe inconsistencies in the magnitude. These inconsistencies are called errors. To categorize and characterize these results and their errors, the researcher can use statistical analysis to determine the quality of the measurements and/or suitability of the methods.
One of the most commonly used statistical quantifiers is the mean, which is the ratio between the sum of the numerical values of all results and the...
One of the most commonly used statistical quantifiers is the mean, which is the ratio between the sum of the numerical values of all results and the...
6.1K
What is Variation?
11.2K
Apart from the measures of central tendency, distribution, outliers, and the changing characteristics of data with time, an important characteristic of any data set is its variation or spread. In some data sets, the data values are concentrated closely near the mean; in others, the data values are more widely spread out from the mean.
The range, standard deviation, standard error, and variance are the different measures of variation.
Range: The range is the difference between its maximum and...
The range, standard deviation, standard error, and variance are the different measures of variation.
Range: The range is the difference between its maximum and...
11.2K
Uncertainty in Measurement: Reading Instruments
37.9K
Counting is the type of measurement that is free from uncertainty, provided the number of objects being counted does not change during the process. Such measurements result in exact numbers. By counting the eggs in a carton, for instance, one can determine exactly how many eggs are there in the carton. Similarly, the numbers of defined quantities are also exact. For example, 1 foot is exactly 12 inches, 1 inch is exactly 2.54 centimeters, and 1 gram is exactly 0.001 kilograms. Quantities...
37.9K
Uncertainty in Measurement: Accuracy and Precision
73.4K
Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value.
73.4K
Data Validation
144
Method validation is a crucial process in analytical chemistry designed to confirm that a given method consistently produces reliable and high-quality results. This process is essential when a method is applied to different sample matrices or when procedural modifications are made, ensuring that the results meet acceptable standards across various applications.
Key parameters for method validation include:
Key parameters for method validation include:
144


