相关实验视频

Updated: Jun 6, 2025

Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay
11:38

Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay

Published on: September 14, 2021

3.3K

组织因子信号修改了G1/S检查点调节者的表达和调节:在受伤和长期炎症期间的影响

Sophie J Featherby1, Eamon C Faulkner1, Camille Ettelaie1

  • 1Biomedical Section, Hull-York Medical School, University of Hull, Hull, HU6 7RX, UK.

Molecular medicine reports
|November 29, 2024
PubMed
概括

组织因子 (TF) 调节细胞循环检查点,影响伤口愈合. 它的度表明细胞损伤,但长时间暴露会导致异常细胞生长,因调节瘤抑制剂.

关键词:
E2F E2F E2F E2F E2F E2F E2F E2F E2F E2F E2F在G1/S检查站.细胞循环中的细胞循环.p14 在ARFF中.p16INKaKa 的意思p21CIP1/WAF1 的使用情况蛋白质酶激活受体 2 的受体.视网母细胞瘤蛋白质是什么组织因子 组织因子这是一种β1-整体蛋白.

更多相关视频

Stab-Wound Mouse Model for Studying Hemorrhage and Inflammation in Traumatic Brain Injury04:03

Stab-Wound Mouse Model for Studying Hemorrhage and Inflammation in Traumatic Brain Injury

Published on: February 21, 2025

286
Pseudofracture: An Acute Peripheral Tissue Trauma Model10:08

Pseudofracture: An Acute Peripheral Tissue Trauma Model

Published on: April 18, 2011

14.7K

相关概念视频

Phases of Wound Repair01:28

Phases of Wound Repair

Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
5.9K
Intracellular Signaling Affects Focal Adhesions01:17

Intracellular Signaling Affects Focal Adhesions

Integrins act both as extracellular input receivers and as intracellular processing activators. As their name suggests, integrins are entirely integrated into the membrane structure. Their hydrophobic membrane-spanning regions interact with the phospholipid bilayer's hydrophobic region. These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors. They activate intracellular response cascades when their effectors are bound and active.
Some...
2.6K
Inflammatory Response01:28

Inflammatory Response

An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
1.8K
Inflammation01:38

Inflammation

Overview
52.7K
TGF - β Signaling Pathway01:16

TGF - β Signaling Pathway

The TGF-β signaling pathway regulates cell growth, differentiation, adhesion, motility, and development. TGF-β ligands that induce TGF-β signaling are synthesized in their latent form. Several proteases or cell surface receptors such as integrins act upon the latent form, releasing the active ligand. There are three types of mammalian TGF-βs: (TGF-β1, TGF-β2, and TGF-β3) that bind as homodimers or heterodimers to TGF-β receptors. The TGF-β receptors...
7.2K
DNA Damage can Stall the Cell Cycle02:37

DNA Damage can Stall the Cell Cycle

In response to DNA damage, cells can pause the cell cycle to assess and repair the breaks. However, the cell must check the DNA at certain critical stages during the cell cycle. If the cell cycle pauses before DNA replication, the cells will contain twice the amount of DNA. On the other hand, if cells arrest after DNA replication but before mitosis, they will contain four times the normal amount of DNA. With a host of specialized proteins at their disposal,cells must use the right protein at...
9.0K