在COVID-19感染和ST段升高中与炎症相关的标志物心肌梗塞心肌梗塞
Nart Z Baytuğan1, Hasan C Kandemir2, Aziz I Çelik3
1Gebze State Hospital, Gebze, Kocaeli, Türkiye - nartzafer@hotmail.com.
Minerva cardiology and angiology
|November 29, 2024
概括
像SII和PLR这样的炎症标志物与ST段升高心肌梗塞 (STEMI) 患者的死亡风险增加有关,特别是COVID-19患者. 这些标记可以帮助预测STEMI患者的结果.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 炎症研究 炎症研究
背景情况:
- 研究炎症标志物与ST段升高心肌梗塞 (STEMI) 之间的联系.
- 评估COVID-19感染对STEMI结果的影响.
- 评估用于心血管事件风险分层的新型炎症标志物.
研究的目的:
- 探索炎症标志物和STEMI之间的关联.
- 为了确定炎症标志物对STEMI患者死亡率的预测值,考虑到COVID-19状态.
主要方法:
- 149名STEMI患者的观察性,单中心,回顾性研究 (2020年1月至2022年11月).
- 系统免疫炎症指数 (SII),系统炎症反应指数 (SIRI),血小板与淋巴细胞比率 (PLR) 和中性粒细胞与淋巴细胞比率 (NLR) 的计算.
- 在COVID-19阳性和阴性STEMI患者组之间的结果的比较.
主要成果:
- 总体而言,住院死亡率为12%.
- 在COVID-19阳性STEMI患者 (24.3%) 中,死亡率明显高于COVID-19阴性STEMI患者 (5.6%).
- SII和PLR被确定为STEMI患者死亡的重要独立风险因素.
结论:
- 系统免疫炎症指数 (SII),系统炎症反应指数 (SIRI),中性粒细胞与淋巴细胞的比率 (NLR) 和血小板与淋巴细胞的比率 (PLR) 是有效的炎症标志物.
- 这些标志物可以预测ST段升高心肌梗塞 (STEMI) 患者的死亡风险.
- 炎症标志物可能在管理STEMI方面发挥关键作用,特别是在COVID-19等病毒感染的背景下.
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