27名患者的结节性性眼表面状新生病:临床表现,管理和结果
Vijitha S Vempuluru1, Anshika Luthra1, Prerna Sinha1
1The Operation Eyesight Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, India.
Seminars in ophthalmology
|November 29, 2024
概括
结节性性眼表面状瘤 (nuOSSN) 是一种侵袭性癌症,由于角膜缩而经常被误诊. 晚期阶段导致全球救援率较低和频繁的复发.
科学领域:
- 眼科医生 眼科 眼科
- 在瘤学瘤学.
- 癌症研究 癌症研究
背景情况:
- 眼表面状瘤 (OSSN) 可以呈现出各种形式.
- 节节性OSSN (nuOSSN) 是一个不太常见但具有攻击性的亚型.
- 早期和准确的诊断对于有效的管理至关重要.
研究的目的:
- 描述nuOSSN.的临床特征,治疗方法和结果.
- 突出诊断挑战和与nuOSSN相关的预后因素.
主要方法:
- 对27名被诊断患有nuOSSN.N的患者进行了回顾性队列研究.
- 在六年内从四级眼科瘤中心收集的数据.
- 对临床表现,管理策略和患者结果的分析.
主要成果:
- 很大一部分患者 (26%) 经历了错误诊断,平均延迟14个月.
- 圆柱状结膜是最常见的部位,瘤经常涉及角膜和硬膜稀释 (分别为56%和37%).
- 瘤阶段从T2到T4不等,治疗方法包括局部化疗,手术,核切除和化. 当地复发发生在11%的治疗患者中,全球救援率较低 (16%).
结论:
- nuOSSN是一种侵袭性的眼部瘤,通常在晚期呈现.
- 角膜缩可能导致误诊,并使治疗复杂化.
- 呈现时的高级阶段与糟糕的地球救援和更高的复发风险有关.
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