在药物诱导的睡眠内镜检查中预测口腔水平的完全集中性崩:对1761例病例的分析
Emily Schoustra1, M Leentjens2, J P van Maanen2
1Department of Otorhinolaryngology- Head and Neck Surgery, OLVG, Jan Tooropstraat 164, Amsterdam, 1061AE, The Netherlands. e.schoustra@olvg.nl.
身体质量指数 (BMI) 与药物诱导睡眠内镜 (DISE) 接受阻塞性睡眠呼吸暂停 (OSA) 患者的完全集中性 palatal 崩 (CCCp) 有关. 然而,单独的BMI并不是CCCP的可靠预测指标,这凸显了在外科选择中需要使用DISE.
科学领域:
- 睡眠医学 睡眠医学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 呼吸系统医学 呼吸系统医学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种常见的睡眠障碍.
- 药物诱导睡眠内镜 (DISE) 识别了上呼吸道崩模式,用于手术候选人选择.
- 在口腔层面的完全同心崩 (CCCp) 是DISE期间评估的特定崩模式.
研究的目的:
- 用患者特征来预测DISE期间CCcp的概率,重点是身体质量指数 (BMI).
- 评估BMI和其他CCCP预测指标的诊断效率.
主要方法:
- 1761名接受了DISE的OSA患者的回顾性审查.
- 使用了后勤回归,接收器操作特征 (ROC) 分析和分类和回归树 (CART) 分析.
- 评估的BMI,子周长,呼吸暂停-呼吸暂停指数 (AHI) 和桃体大小作为预测指标.
主要成果:
- 在22.3%的患者中观察到CCCp.
- 更高的BMI,子周长,AHI和身高与CCCP有关.
- ROC分析显示,仅BMI的预测值有限 (AUC为0.65-0.73).
- 添加其他预测因素提高了模型预测CCCP的性能.
结论:
- 增加的BMI和CCCP之间存在关联,但BMI不是唯一准确的预测指标.
- 由于CCCP的多因素性质,需要进行全面的评估.
- DISE对于评估CCCP和指导临床决策至关重要,特别是对于低分泌神经刺激疗法.
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