使用大麻和CBD睡觉:一个更新的评论
Isobel Lavender1,2, Grace Garden1,3,4,5,6, Ronald R Grunstein1,3,4,5,6
1Centre for Sleep and Chronobiology, Woolcock Institute of Medical Research, Macquarie University, Sydney, New South Wales, Australia.
Current psychiatry reports
|November 29, 2024
概括
基于大麻的治疗方法对睡眠障碍很受欢迎,但目前的研究表明,对其有效性和安全性的高质量证据有限. 需要更严格的临床试验来支持它们的使用.
科学领域:
- 睡眠医学 睡眠医学
- 药理学 药理学是指药理学的学科.
- 大麻素研究 研究 大麻素研究
背景情况:
- 大麻sativa及其大麻素被广泛用于寻求药物治疗睡眠障碍的患者.
- 现有的审查表明,关于大麻素在各种疾病中的有效性和长期安全性的高质量证据很少.
- 本综述侧重于最近的研究,评估专门针对睡眠障碍的大麻素治疗方法.
研究的目的:
- 提供最新的回顾,最近的原始研究,对大麻素为基础的疗法,睡眠障碍.
- 评估当前使用大麻素治疗失眠和睡眠呼吸暂停等疾病的证据基础.
- 为了识别用于睡眠的大麻素研究的新兴趋势.
主要方法:
- 进行了系统的搜索,以确定最近关于大麻素和睡眠障碍的原始研究研究.
- 包括评估失眠,主观睡眠障碍,阻塞性睡眠呼吸暂停,REM睡眠行为障碍和不安腿综合征的研究.
- 分析了大麻素研究的趋势,包括小大麻素的使用,分散的研究方法和客观的结果措施.
主要成果:
- 确定了21项评估大麻素对一系列睡眠障碍的最新研究.
- 观察到的趋势是研究小卡纳比诺因和采用分散的研究方法的研究.
- 注意到最近的临床试验中客观措施的使用增加,评估大麻素对睡眠的有效性.
- 目前关于大麻素在睡眠障碍中使用的证据基础与它们的广泛应用不一致.
结论:
- 支持大麻素广泛用于睡眠障碍的证据仍然不足.
- 对于设计精良,资金充足,样本大小足够,持续时间较长的临床试验,有着显著且日益增长的需求.
- 未来的研究应该专注于生成可靠的数据,以指导临床医生和患者在治疗性使用大麻素的睡眠条件.
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