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Updated: Jun 15, 2025

Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells
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氧化还原传感器KEAP1通过防止过度激活,促进T细胞适应慢性抗原刺激

Ziang Zhu1,2, Ying Luo1, Guohua Lou3

  • 1Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Science immunology
|November 29, 2024
PubMed
概括

在慢性病毒感染期间,KEAP1-NRF2通路对于维持干状CD8+T细胞至关重要. 这一途径调节T细胞扩张,持久性和免疫检查点分子,确保长期免疫力.

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