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Updated: Jun 6, 2025

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PLCγ2的晶体和冷EM结构揭示了自抑制中的动态域间识别

Young-Cheul Shin1, Ashlee Marie Plummer-Medeiros1, Alison Mungenast2

  • 1Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

Science advances
|November 29, 2024
PubMed
概括

结构洞察力揭示了脂酶C玛2 (PLCγ2) 是如何调节的. 在其抑制区域的动态相互作用和与纤维细胞生长因子受体1 (FGFR1) 的结合澄清了PLCγ2活性调节.

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