肌肉力量,内皮功能和认知障碍:最先进的技术
Yuri Sanchez-Martinez1, Jose P Lopez-Lopez1, Isabela Gomez-Montoya1
1Masira Research Institute, Universidad de Santander (UDES), Bucaramanga, Colombia.
衰老会削弱骨肌肉,损害内皮功能,导致认知能力下降. 通过抵抗训练来保持肌肉力量可以保护大脑健康,并延迟老年人的认知障碍.
科学领域:
- 老年学和神经科学研究
- 心血管生物学 心血管生物学
- 骨肌肉生理学 骨肌肉生理学
背景情况:
- 人口老龄化正在增加,带来诸如认知障碍和心血管疾病等挑战.
- 与年龄相关的骨肌肉质量和力量的下降与认知障碍有关.
- 连接肌肉功能障碍,内皮功能障碍和认知障碍的机制尚未完全理解.
研究的目的:
- 审查将衰老,骨肌肉和内皮功能障碍与认知障碍联系在一起的细胞和分子机制.
- 探索力量训练如何保护大脑功能,延迟认知衰退.
主要方法:
- 文献综述专注于细胞和分子机制.
- 关于衰老,骨肌功能,内皮功能和认知健康的研究分析.
- 检查抗力训练的潜在好处.
主要成果:
- 衰老会改变骨肌肉和内皮功能,增加氧化应激,炎症和线粒体功能障碍.
- 这些变化会降低肌肉力量,促进内皮功能障碍,破坏血脑屏障,损害神经细胞.
- 抵抗训练可以改善内皮功能,血液动力学和大脑可塑性,可能延迟认知障碍.
结论:
- 肌肉和内皮功能与年龄相关的下降加速了认知障碍.
- 通过抵抗训练等干预措施维持骨肌肉功能,有望预防大脑衰老和相关疾病.
更多相关视频
08:35Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
Published on: August 17, 2022
09:04Skeletal Muscle Neurovascular Coupling, Oxidative Capacity, and Microvascular Function with 'One Stop Shop' Near-infrared Spectroscopy
Published on: February 20, 2018
相关概念视频
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Exercise and Muscle Performance
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Pathophysiology of Cardiac Performance
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
