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健康狗中风体积的心声学估计:可比性,参考间隔和可重现性
K E Davis1, L C Visser2, J A Boon2
1James L. Voss Veterinary Teaching Hospital, College of Veterinary Medicine & Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
概括
狗的心声图中风体积估计是不可互换的. 对于分流和反体积的新参考间隔有助于评估犬病患者的疾病严重程度.
科学领域:
- 兽医心脏病学 兽医心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心血管生理学心血管生理学
背景情况:
- 估计狗的中风体积 (SV) 对于评估心脏功能至关重要.
- 之前的研究没有全面比较不同解剖部位的SV估计值,也没有为相关指数建立参考间隔.
研究的目的:
- 为了比较从各种解剖位置获得的中风体积 (SV) 估计,使用健康狗的心声回声学.
- 在大型犬种群中,建立对冲量 (ShuntVol) 和吐量 (RegVol) 的参考间隔.
主要方法:
- 90只健康的狗进行了心声扫描,以测量肺 (SVPV),大动脉 (SVAV),心交 (SVMV) 和左心室 (SVLV_RPLx,SVLV_Ap4Ch) 的SV.
- 可复制性通过相同和不同的操作人员重复测量来评估.
- 为ShuntVol和RegVol生成了布兰德-阿尔特曼分析和95%的参考间隔.
主要成果:
- 声心动图SV估计是不可互换的,在不同的测量站点之间表现出广泛的协议限制.
- 在大多数反体积计算中观察到显著的固定偏差 (RegVolLV_RPLx是例外).
- 对于ShuntVol (-0.85-0.64毫升/公斤),RegVolLV_RPLx (-0.65-0.58毫升/公斤),RegVolLV_Ap4Ch (-0.77-0.52毫升/公斤) 和RegVolMV (-0.91-1.06毫升/公斤) 建立了参考间隔.
结论:
- 来自不同部位的回心心电图中风体积测量不能互换,并且显示出相当大的变化.
- 已确立的分离和反体积的参考间隔为评估心脏病患者犬的疾病严重程度提供了有价值的工具.
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