临床医生处方实践涉及酒精使用障碍药物治疗
Alene Kennedy-Hendricks1, Alisa B Busch2, Hocine Azeni3
1Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
American journal of preventive medicine
|November 29, 2024
概括
大多数临床医生对酒精使用障碍 (AUD) 处方的药物很少. 精神病医生和高级实践提供者比初级保健医生更有可能开处方这些药物. 需要进一步的研究.
科学领域:
- 成 药物 药物 药物 药物
- 药物治疗 药物治疗
- 医疗保健服务研究 医疗服务研究
背景情况:
- 酒精使用障碍 (AUD) 在美国构成了重大的公共卫生负担.
- 尽管有有效的治疗方法,但对AUD (MAUD) 的药物使用不足.
- 临床医生对MAUD的处方模式存在有限的研究.
研究的目的:
- 分析临床医生对FDA批准的药物的处方实践,用于治疗酒精使用障碍.
- 确定与处方MAUD的数量和类型相关的因素.
- 了解药物治疗在AUD治疗中的应用.
主要方法:
- 2016-2021年电子健康记录的横截面分析.
- 确定的临床医生向患有AUD的患者开处方纳尔特雷,阿坎普罗沙特或迪苏尔菲拉姆.
- 使用后勤回归来检查临床医师特征和处方模式之间的关联.
主要成果:
- 59%的临床医生每年只给一个病人开MAUD.
- 与初级保健医生相比,精神病医生和高级实践提供者更有可能给多个患者开处方.
- 诊断患有物质使用障碍的患者比例较高的临床医生更有可能开处方MAUD和多种类型的药物.
结论:
- 大多数临床医生不经常开处方MAUD.
- 系统性变化是必要的,以加强对AUD的药理疗法的使用.
- 干预措施应考虑初级保健医生,他们经常与AUD患者接触.
更多相关视频
相关概念视频
CNS Depressants: Alcohol and Nicotine
174
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
174
Depressants
99
Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
99
Drug Therapy
39
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
39
Drug Abuse and Addiction: Pharmacological Phenomena
444
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
444
Substance Use Disorders Affecting Sleep
160
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
160
Psychosis: Goals of Pharmacotherapy
104
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
104


