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坦辛I作为天然Cu (II) 离子体的鉴定

Ya-Long Zheng1, Yuan Ji2, Yan Li2

  • 1State Key Laboratory of Applied Organic Chemistry, Lanzhou University, 222 Tianshui Street S., 730000, Lanzhou, Gansu, China; Medicine College of Pingdingshan University, 467000, Pingdingshan, Henan, China.

Free radical biology & medicine
|November 29, 2024
PubMed
概括

坦辛I,一种天然的o-,作为一种新的铜(II) 离子体,在癌细胞中选择性地积累铜. 这破坏了氧化还原平衡,产生了活性氧物种,并诱导了癌细胞的亡.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.铜铜 铜铜 铜铜离子体离子体氧化还原失衡是指氧化还原失衡一个tanshinone一个人.这是一种o-氨酸 (o-quinone).

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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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