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Updated: Jun 6, 2025

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CBX7抑制剂会影响H3K9甲基转移酶调节的白血病细胞中的基因抑制

Anne P de Groot1, Huong Nguyen2, Jacobine S Pouw3

  • 1European Research Institute for Biology of Ageing (ERIBA), University Medical Center Groningen, Groningen, The Netherlands; Sanquin Research, Amsterdam, the Netherlands.

Experimental hematology
|November 29, 2024
PubMed
概括

在白血病中,Polycomb组蛋白CBX7与H3K9甲基转移酶相互作用. 仅仅抑制CBX7就会重新激活基因表达,并显示出白血病治疗中的治疗潜力.

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