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甲状腺功能障碍与甲状腺功能障碍相关的猫症:一个说明案例和已发表病例的系统审查
Jeremy R Chaikind1, Hannah L Pambianchi2, Catherine Bledowski3
1Inova Behavioral Health Services, Inova Fairfax Medical Campus, Falls Church, VA; Department of Psychiatry, The George Washington University, Washington, DC; Department of Psychiatry & Behavioral Science, University of Minnesota, Minneapolis, MN.
甲状腺风暴期间可能发生甲状腺炎,有时由神经乱药物加剧. 临床医生应该考虑这一关联,并尽量减少在患有甲状腺功能障碍的患者中使用神经乱药.
科学领域:
- 内分泌学 在内分泌学.
- 精神病学是一个精神病学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 在医疗环境中,猫症往往被忽视,导致治疗延迟,以及神经麻醉药的潜在危害.
- 甲状腺风暴很少与catatonia有关,现有病例报告的综合仅限.
研究的目的:
- 报告甲状腺风暴期间甲状腺炎的病例,后的haloperidol的管理.
- 系统地审查和分析先前报告的甲状腺功能障碍症相关的猫病例.
主要方法:
- 介绍了一个37岁的女性患有甲状腺功能障碍,双相情感障碍和甲状腺风暴的病例,该病例在haloperidol后发生了catatonia.
- 使用OVID Medline,PsycINFO和Embase数据库进行了系统的文献审查,遵循PRISMA指南.
主要成果:
- 确定了与甲状腺功能障碍症相关的十七例白色炎症病例.
- 在29%的病例中,观察到神经质药,特别是多巴胺抗剂,通常是低剂量.
- 常见因素包括精神病症状 (41%) 和甲状腺自身抗体 (41%) 的病史.
结论:
- 甲状腺功能障碍可能会增强多巴胺阻塞,这表明在这个人群中使用神经乱药要谨慎.
- 甲状腺功能障碍症中猫的替代机制包括直接的甲状腺毒性作用或自身免疫反应.
- 对于临床医生来说,在甲状腺风暴中对甲状腺炎的意识至关重要,无论神经乱药的使用情况如何.
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