穿越中的血栓和肺栓塞:迫切需要提高认识和采取行动
Mario Di Marino1, Vincenzo Cicchitti2, Umberto Ianni3
1Department of Neuroscience and Imaging and Clinical Sciences, Gabriele d'Annunzio University of Chieti and Pescara, Chieti, Abruzzo, Italy.
Heart (British Cardiac Society)
|November 29, 2024
概括
心脏中转血栓 (CiT) 是急性肺栓塞 (PE) 患者的一个未被认可的疾病. 肺栓塞反应小组 (PERT) 的早期鉴定和多学科管理对于改善结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 紧急医疗 紧急医疗
背景情况:
- 急性肺栓塞 (PE) 呈现出各种不同的临床表现,从无症状的发现到致命的结果.
- 目前的指导方针提供基于患者的风险和血液动力学状况的各种管理策略.
- 在右心脏内发生的转移性血栓 (CiT) 是一个未被认可的实体,与显著的死亡率和急剧的临床衰退有关.
研究的目的:
- 突出在PE患者中识别CiT的挑战.
- 提出一个算法,强调肺栓塞反应小组 (PERT) 在管理CiT方面的作用.
- 概述PE与CiT的诊断和治疗策略.
主要方法:
- 审查现有关于CIT检测和管理的文献.
- 关于涉及PERT的管理算法的建议.
- 讨论除了抗凝血之外的先进治疗选择.
主要成果:
- CiT检测稀少,但始终与预后不佳有关.
- 建议在PE病例中对CiT进行系统的调查和记录.
- 涉及PERT的结构化方法可促进及时诊断和量身定制的管理.
结论:
- 患有PE和CiT的患者需要谨慎监测和迅速升级治疗.
- 多学科的PERT参与对于优化护理至关重要.
- 应考虑积极的治疗策略,包括血栓溶解,栓塞切除和导管导向疗法,以治疗CiT的PE.
关键词:
肺栓塞是因为肺栓塞.相关概念视频
Clot Retraction and Fibrinolysis
4.1K
After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
4.1K
Pneumothorax-I
170
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
170
Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors
469
Antiplatelet drugs emerge as frontline defenders against the insidious threat of thromboembolic diseases, where abnormal clots obstruct vital blood vessels. These drugs stand as bulwarks, inhibiting platelet aggregation and clot formation, thereby mitigating the risk of life-threatening conditions like myocardial infarction, coronary artery disease, and thrombotic strokes.
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
469
Anticoagulant Drugs: Low-Molecular-Weight Heparins
623
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
623
Disorders of Hemostasis
710
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
710
Radiological Investigation III: Pulmonary Angiogram and PET Scan
86
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
86


