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高血糖和2型糖尿病与慢性鼻炎患者的术后复发有关
Xuan Yuan1,2,3,4, Lai Meng1,2,3,4, Liyuan Liu5
1Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital of Central South University, 87 Xiangya Road, Kaifu District, Changsha, 410008, People's Republic of China.
禁食血糖 (FBG) 和2型糖尿病 (T2DM) 的升高增加了手术后慢性鼻炎 (CRS) 复发的风险. 慢性呼吸系统持续时间和过敏性鼻炎也是显著的危险因素.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 内分泌学 在内分泌学.
- 外科手术的结果
背景情况:
- 慢性鼻炎 (CRS) 是一种影响生活质量的常见疾病.
- 术后复发仍然是CRS管理的一个重大挑战.
- 代谢因素,如空腹血糖 (FBG) 和2型糖尿病 (T2DM) 在CRS复发中的作用尚未完全阐明.
研究的目的:
- 调查FBG水平和T2DM与术后CRS复发风险之间的关联.
- 确定其他潜在的CRS复发风险因素.
主要方法:
- 对1163名接受手术的CRS患者进行了回顾性队列研究.
- 根据T2DM状态和复发情况对患者进行分类.
- 使用了卡普兰-梅尔生存分析和后勤回归模型.
主要成果:
- 与非T2DM组相比,T2DM组的复发率明显高.
- 在复发性CRS患者中观察到更高的FBG水平和T2DM患病率.
- 确定T2DM作为复发的独立风险因素;FBG,CRS持续时间和过敏性鼻炎也相关.
结论:
- 升高的FBG和T2DM是术后CRS复发的独立风险因素.
- 慢性神经复发症的持续时间和过敏性鼻炎是导致复发的潜在因素.
- 研究结果表明,代谢控制和并发症的管理对于改善CRS手术结果至关重要.
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