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12毫米对10毫米金属支架用于恶性胆道阻塞:系统性审查和元分析

Alonzo Armani Prata¹, Matheus Vanzin Fernandes², Ana Carolina Covre Coan³

¹Federal University of Espírito Santo, Av. Mal. Campos, 1468 - Maruípe, Vitória, ES, 29047-105, Brazil. alonzo.prata@edu.ufes.br.

Digestive diseases and sciences

|November 29, 2024

概括

较大的金属支架 (12毫米) 与10毫米支架相比,显著改善恶性胆道阻塞的结果. 这包括更长的通透性和减少阻塞,不增加不良事件.

科学领域:

胃肠病学胃肠病学
干预性内镜检查是干预性的内镜检查.
在瘤学瘤学.

背景情况:

恶性胆道阻塞通常用内镜金属支架治疗.
支架堵塞和迁移是常见的并发症.
更大的直径支架可能会提供更好的结果.

研究的目的:

为了比较10毫米与12毫米覆盖金属支架在治疗复发性不可切割的胆道阻塞方面的疗效.
评估结果,如复发的胆道阻塞和支架通透性.

主要方法:

对PubMed,Embase和Cochrane数据库进行系统审查.
包括一个随机临床试验和四个队列研究 (520名患者).
分析的主要结局:复发性胆道阻塞 (RBO) 和时间到RBO (TRBO).

主要成果:

12毫米支架与更长的RBO时间 (HR1.72) 和较低的RBO发生率 (RR0.59) 有关.
12毫米支架显示了支架阻塞率的降低 (RR 0.52).
没有观察到支架迁移或不良事件的显著差异.

结论:

12毫米金属支架显著提高了在复发的不可切割的胆道阻塞中支架的通透性.
更大的直径支架减少了反复发生的胆道阻塞和支架阻塞的发生率.
支架迁移和不良事件发生率在10毫米和12毫米支架之间是可比的.

关键词:

胆管胆管是胆管中的一个通道.胆道疾病胆道疾病胆固醇的形成胆固醇的形成新生体新生体新生体自行扩展的金属支架.

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