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相关概念视频

Symbiosis00:58

Symbiosis

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Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
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The Scientific Method01:32

The Scientific Method

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The scientific method is a detailed, empirical problem-solving process used by biologists and other scientists. This iterative approach involves formulating a question based on observation, developing a testable potential explanation for the observation (called a hypothesis), making and testing predictions based on the hypothesis, and using the findings to create new hypotheses and predictions.
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...
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Distribution and Dispersion00:54

Distribution and Dispersion

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To understand intra-specific interactions in populations, scientists measure the spatial arrangement of species individuals. This geographic arrangement is known as the species distribution or dispersion. Highly territorial species exhibit a uniform distribution pattern, in which individuals are spaced at relatively equal distances from one another. Species that are highly tied to particular resources, such as food or shelter, tend to concentrate around those resources, and thus exhibit a...
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Formation of Species01:31

Formation of Species

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Speciation describes the formation of one or more new species from one or sometimes multiple original species. The resulting species are discrete from the parent species, and barriers to reproduction will typically exist. There are two primary mechanisms, speciation with and without geographic isolation—allopatric and sympatric speciation, respectively.
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Diversity in Cell Signaling Responses01:22

Diversity in Cell Signaling Responses

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The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity. 
Graded and Abrupt Responses
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Transmission Electron Microscopy01:15

Transmission Electron Microscopy

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In 1931, physicist Ernst Ruska—building on the idea that magnetic fields can direct an electron beam just as lenses can direct a beam of light in an optical microscope—developed the first prototype of the electron microscope. This development led to the development of the field of electron microscopy. In the transmission electron microscope (TEM), electrons are produced by a hot tungsten element and accelerated by a potential difference in an electron gun, which gives them up to 400...
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科学中的综合:策划的协作合作.

David B Hurry1, Elena S Izmailova1, Simon Davies2

  • 1Koneksa Health, New York, New York, USA.

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概括

数据综合提供了一个开发数字化措施的新模式. 这种精心策划的合作使生物制药赞助商能够更快地启动研究和实时数据流.

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科学领域:

  • 数字健康数字健康
  • 临床试验方法论 临床试验方法论
  • 数据科学是数据科学.

背景情况:

  • 数字化措施需要专门的临床研究来开发和验证.
  • 目前的模式包括单一赞助商研究或竞争前合作.

研究的目的:

  • 为数字测量开发和验证提出一个替代模型.
  • 突出数据综合在临床研究中的优势.

主要方法:

  • 引入数据综合作为一个策划的协作模式.
  • 将技术提供商作为创始成员与生物制药赞助商和利益相关者一起参与.

主要成果:

  • 与传统模型相比,数据综合可以实现更快的研究启动.
  • 这种模型可以从数字测量器进行实时数据流.

结论:

  • 数据综合提供了一个可行的和高效的替代数字测量验证.
  • 该模型增强了临床研究中的协作和数据可访问性.