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通过Cefixime注入的绿色ZnO纳米板具有增强的生物潜力

Amna Munsaf^1,2, Muhammad Naeem Ahmed¹, Ihsan Ul Haq³

¹Department of Chemistry, The University of Azad Jammu & Kashmir, Muzaffarabad, Pakistan.

Microscopy research and technique

|November 30, 2024

概括

绿色合成的氧化物纳米板块注入cefixime显示出强大的抗微生物和抗氧化特性. 这些新型纳米材料为打击抗生素耐药性和推进生物医学应用提供了有前途的解决方案.

科学领域:

材料科学材料科学材料科学
纳米技术纳米技术
生物医学工程生物医学工程

背景情况:

抗生素耐药性构成了全球严重的健康威胁,需要新的治疗方法.
氧化纳米板块 (ZnO NPts) 正在研究它们的抗菌潜力.
塞菲西姆是一种第三代类抗生素.

研究的目的:

为了合成注入cefixime的绿色合成氧化纳米板块 (ZnO NPts).
评估这些功能化 ZnO NPts 的增强生物潜力.
研究它们的抗真菌,细胞毒性和抗氧化活性.

主要方法:

绿色合成ZnO NPts. 的方法
在ZnO NPT上注入Cefixime.
使用UV-Vis,FTIR,XRD,SEM,TEM,EDS和DLS进行表征.
生物评估包括抗真菌,盐水细胞毒性和抗氧化剂测试 (TAC,TRP,DPPH).

主要成果:

成功合成和表征CEFIXIME注入的 ZnO NPts.
与纯 ZnO NPts 和单独使用的 cefixime 相比,增强的抗真菌活性.
对Artemia salina幼虫具有显著的细胞毒性.
在多项测试中显示出明显的抗氧化活性.

结论:

用Cefixime注入的ZnO NPts表现出优越的生物特性.
这些纳米材料为开发新的抗微生物和治疗剂提供了一个有希望的平台.
该研究强调了功能化纳米材料在应对公共卫生挑战方面的潜力.

关键词:

在NPts NPts中.抗真菌活动的抗真菌活性.cefixime cefixime是什么意思细胞毒性细胞毒性绿色合成是一种绿色合成.氧化氧化的使用方法

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