马来西亚耐药结核病:流行率,特征和治疗结果
M Y Sidek1, M F Kamarul Zaman2, N H Nik Rosmawati2
1Universiti Sains Malaysia, School of Medical Sciences, Department of Community Medicine, Kelantan, Malaysia. dryusofs@usm.my.
The Medical journal of Malaysia
|November 30, 2024
概括
在马来西亚,从2016年到2020年,耐药结核病 (DR-TB) 的患病率有所增加. 56.7%的病例出现了良好的结果,但42.1%的病例出现了不良结果,这凸显了改善公共卫生干预措施的必要性.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 耐药结核病 (DR-TB) 是一个重要的全球健康问题.
- 马来西亚观察到DR-TB病例的增加,需要进行本地化趋势分析.
- 高发病率和高死亡率凸显了应对抗药性结核病的紧迫性.
研究的目的:
- 确定2016年至2020年期间马来西亚DR-TB的流行率.
- 描述DR-TB患者的人口统计和临床特征.
- 为了评估DR-TB病例的治疗结果.
主要方法:
- 从塞兰戈尔和吉隆坡的结核病登记处获得的二次数据的回顾性审查.
- 分析了2016年至2020年注册的DR-TB病例.
- 使用SPSS版本27进行描述性统计分析.
主要成果:
- 耐药结核病患病率从每10万人口中的0.27上升至1.79 (2016-2020年).
- 大多数患者是男性 (70.7%),马来西亚人 (79.3%),平均年龄为40.96岁.
- 在56.7%的病例中取得了有利的治疗结果,而42.1%的病例有不利的治疗结果 (失去了随访,死亡,治疗失败).
结论:
- 随着DR-TB病例的增加,需要加强公共卫生干预和利益相关方的合作.
- 调查结果为决策者提供指导,以加强耐药结核病控制和预防战略.
- 有针对性的战略对于减轻DR-TB日益增加的负担至关重要.
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