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在电子健康记录中描述药物诱导的口吃

Dillon G Pruett¹, Christine Hunter², Alyssa Scartozzi¹

¹Vanderbilt Genetics Institute, Vanderbilt University Medical Center, USA.

Journal of communication disorders

|November 30, 2024

概括

这项研究在使用电子健康记录的22名患者中确定了与药物诱导的口吃相关的18种药物. 抗发作药物,中枢神经系统兴奋剂和抗抑郁药物是最经常涉及的,托皮拉是最常见的犯罪者.

科学领域:

神经学神经学
药理学药理学是指药理学的学科.
语音语言病理学语言病理学

背景情况:

药物诱导的口吃是一种由药物物质引起的获得性语言障碍,与发育性口吃类似.
以前的研究依赖于有限的案例研究和不良事件报告.
电子健康记录 (EHR) 为在临床环境中识别药物诱导的口吃提供了宝贵的资源.

研究的目的:

使用EHR数据识别和分类与药物诱导口吃相关的药物.
分析涉及药物和患者病例的特征.

主要方法:

从一个主要的大学医疗中心进行了对EHR的系统审查.
40个疑似药物诱导的口吃病例,从先前对300万个人的审查中确定,被全面评估.
收集的数据包括药物名称,类别,作用机制,证据水平,治疗方法和口吃的进展.

主要成果:

18种不同的药物与22个人的口吃有关.
涉及的最常见的药物类别是抗发作药物,中枢神经系统刺激剂和抗抑郁药.
托皮拉 (Topamax) 是与口吃相关的最常见的药物.

结论:

这项研究是首次在临床环境中分析卫生系统数据,分析导致口吃的药物.
鉴定了各种各样的药物,扩展了以前的病例报告.
对与药物相关的语音流性变化的增强EHR报告对于进一步的研究至关重要.

关键词:

获得的口吃获得的口吃药物诱发的口吃是因为药物.电子健康记录电子健康记录语音运动通道的通道

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