老年营养风险指数与45岁及以上美国成年人肉症之间的关联
Wenjun Hao1, Xiajie Huang2, Rongyuan Liang1
1Department of Bone and Joint Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Nutrition (Burbank, Los Angeles County, Calif.)
|November 30, 2024
概括
老年营养风险指数 (GNRI) 预测45岁以上的成年人患有肉症. 较高的GNRI水平与较低的麻症发病率有关,这表明其具有保护作用.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 萨科佩尼亚严重影响公众健康和经济.
- 老年营养风险指数 (GNRI) 是慢性疾病的公认预测指标.
- 了解营养在肉症中的作用对于老年人的健康至关重要.
研究的目的:
- 调查老年营养风险指数 (GNRI) 与皮病患病率之间的相关性.
- 确定GNRI是否是老年人肉症的独立预测因子.
- 探索关系的性质 (线性/非线性) 并确定潜在的值.
主要方法:
- 使用国家健康和营养检查调查 (2009-2018) 数据对4,709名成年人 (≥45岁) 的横截面研究.
- 分类为高GNRI和低GNRI组;通过骨肌肉指数评估的肉症.
- 多变量逻辑回归和受限制立方支线 (RCS) 分析,以检查GNRI的相关性和值效应.
主要成果:
- 与低GNRI组 (17.7%) 相比,高GNRI组 (13.2%) 的麻症发病率较低.
- GNRI是肉症的显著独立预测因子 (OR:0.57;p=0.001),GNRI减少发生率增加.
- 观察到非线性反向关系 (p=0.033),GNRI=91.935的值;特定的子组显示敏感性增加.
结论:
- 在45岁及以上的美国成年人中,GNRI是 Sarcopenia 的可靠预测指标.
- 在GNRI和肉症之间存在非线性反向关系,值为91.935.
- 这些发现突显了营养状况在预防皮病方面的重要性,正如GNRI所指出的那样.
相关概念视频
01:29Bone Disorders
3.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.4K
01:28Anorexia Nervosa
46
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
46
01:26Aging
37
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
37