加速相对比磁共振成像使用分辨率增强生成对抗神经网络
Manuel A Morales1, Fahime Ghanbari1, Ömer Burak Demirel1
1Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
概括
超高分辨率技术CRISPFlow加速了心血管磁共振成像,以量化血液流量. 它有效地恢复了图像分辨率,使得血液流动动态的评估更快,更准确.
科学领域:
- 医疗成像医学成像
- 心血管成像 - 心血管成像
- 人工智能在医学中的应用
背景情况:
- 心血管磁共振 (CMR) 相对比对于量化血液流动至关重要.
- 目前用于相对比成像的方法可能耗时.
- 开发加速成像技术对于改善临床工作流程至关重要.
研究的目的:
- 开发和验证CRISPFlow,用于线内超分辨率的复杂差异重建.
- 在CMR中使用生成对抗网络加速相位对比成像.
- 评估CRISPFlow用于血液流量量化的准确性和效率.
主要方法:
- 基于超级分辨率生成对抗网络的CRISPFlow在2020年追溯CMR数据集上接受了培训.
- 合成的低分辨率图像 (7.5 × 1.9 mm2) 用于训练CRISPFlow以恢复更高的空间分辨率.
- 预期验证涉及54名参与者,将CRISPFlow与标准GRAPPA加速成像 (2.3 × 1.9 mm2) 进行比较.
主要成果:
- 在所有情况下,CRISPFlow成功重建了图像,与未增强的图像相比,明显减少了模糊.
- 使用CRISPFlow实现的图像清晰度与更高分辨率采集 (2.5 × 1.9 mm2和2.3 × 1.9 mm2) 相似.
- 观察到CRISPFlow和GRAPPA对大动脉流量参数 (前进体积,反体积和分数) 的测量与强相关性 (r > 0.90) 之间有很好的一致性.
结论:
- CRISPFlow显示了加速相对照CMR采集的巨大潜力.
- 该技术可以更快地量化血液流量,而不会影响准确度.
- CRISPFlow代表了心血管成像技术的一个有前途的进步.
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